Stage 1 – Intensive depigmentation carried out at the clinic
The peel features a unique and potent combination of ingredients which increase cell renewal and treat the root cause of pigmentation. Developed exclusively by Mesoestetic, the [meso] Intimate System ensures maximum efficacy by integrating active ingredients that work alongside an innovative encapsulation system. This allows for controlled action, high skin tolerability, moisturising and repairing, and long-term maintenance of active ingredient effects. [GL] Inflamm, also exclusive to Mesoestetic, helps control inflammation, enhance progressive depigmentation, and support the skin’s defence mechanisms for reduced hypersensitivity reactions and restored skin balance.
Once applied to the intimate area, the peel is left on for 3-4 hours. After removal, a hydrating and soothing mask is applied over the treated area and left on for 10-15 minutes.
Stage 2 – At-home use treatment
Results are maintained with an at-home, daily use Depigmenting Gel Cream. Using ingredients such as Kojic Acid, Phytic Acid and Salicylic Acid, It treats and regulates genital hyperpigmentation, enhances elasticity, protects and moisturises, and improves skin barrier function of the vulval epithelium. Clinical results have shown a 60% reduction in pigmentation and 27% decrease in transepidermal water loss (TEWL).
Dermamelan® Intimate is a professional depigmentation treatment designed to reduce hyperpigmentation in delicate areas such as the genital-perineal zone, inner thighs, groin, and perianal region. It combines a powerful in-clinic peel with a tailored at-home maintenance program for long-lasting results.
This treatment is safe for use on:
Dermamelan® Intimate is suitable for all skin types and tones. It’s especially beneficial for those experiencing pigmentation due to:
-
Hormonal changes (pregnancy, menopause)
-
Friction or tight clothing
-
Ageing
-
Inflammation or irritation
Most patients see excellent results after just one session, but depending on the severity of pigmentation and individual skin response, additional treatments may be recommended.
You may feel mild warmth, tingling, or a slight stinging sensation during application, but it is generally well tolerated. Any post-treatment discomfort (like redness or tightness) typically subsides within 1–2 days.
Clinical results have shown:
-
Up to 60% reduction in pigmentation
-
Improved skin tone and texture
-
27% decrease in transepidermal water loss (TEWL), indicating stronger, healthier skin
Visible results often begin within 7–10 days, with full results developing over 3–4 weeks.
There’s minimal downtime. You might experience some:
You can resume normal activities, but must avoid:
-
Tight clothing
-
Hot baths, pools, or saunas
-
Intimate hair removal for 7–45 days depending on the type
-
Sun exposure
With proper aftercare and use of the at-home Depigmenting Gel Cream, results can be long-lasting. Maintenance treatments may be needed depending on your skin type and lifestyle.
Yes. The treatment has been specifically formulated for use on delicate areas. It’s dermatologically and gynecologically tested, with high skin tolerability thanks to its innovative delivery system and anti-inflammatory ingredients.
No. The treatment is not recommended during pregnancy or breastfeeding due to hormonal fluctuations and lack of safety data for these conditions.
Immediately After Treatment (First 24–48 Hours)
- Redness & Sensitivity: It’s normal to experience mild redness, warmth, or a tingling sensation—similar to a light sunburn.
- Avoid Washing the Area: Do not wash or apply any products for the first 12 hours post-treatment unless advised by your clinician.
- Wear Loose Clothing: Opt for breathable, cotton underwear and avoid tight clothing to prevent friction and irritation.
During the Peeling Phase (Days 2–7)
- Peeling & Flaking: Light peeling or dryness may begin around Day 3. Do not pick or scrub the skin—let it shed naturally.
- Moisturise Regularly: Use only the recommended soothing or hydrating cream to reduce dryness and support skin recovery.
- No Hair Removal: Waxing and laser should be avoided for 45 days. Shaving can be carried out after 7 days
- Avoid exercise for up to 10 days to avoid friction
At-Home Maintenance Phase
- Daily Use of Depigmenting Gel Cream: Begin applying the prescribed gel cream 48 hours post-treatment, as instructed.
- Apply Once Daily (Evening) to clean, dry skin.
- Follow with a hydrating product if recommended.
- Consistency is Key: Use the product continuously for the duration advised by your practitioner to prevent recurrence and maintain results.
